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© Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology, 2019
Locum Consultant Cellular Pathologist, Worcester Royal Hospital, Worcester, UK
Consultant respiratory medicine, Northwick Park Hospital/Imperial College healthcare NHS Trust
M.A. Montero Fenandez
Consultant Thoracic Pathologist, Manchester University Foundation trust
Consultant Cellular Pathologist, North West London Pathology, based at Imperial College Healthcare NHS Trust
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Pleural chondroid metaplasia in a background of IgG4 plasma cell rich chronic inflammatory infiltrate: report of a rare case with review of literature
Vol 111 No 4 (2019): Pathologica - Issue 4 - December 2019
Published: Dec 19, 2019
Mesothelial reactive and degenerative changes secondary to inflammatory conditions, toxin exposure, neoplastic and non-neoplastic disease are often encountered in routine histopathology practice. Herein, we report a very rare case of pleural chronic inflammation with features suggestive for IgG4-related disease associated with the formation of a nest of mature, benign looking cartilage in the pleura of a middle age male patient. The review of the pertinent literature reveals that to date, only few cases of chondroid metaplasia or benign tumor (choristoma) are reported in mesothelium and only occasionally in this change is found in the pleura.