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© Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology, 2019
Pathology Unit, St Anna Hospital (ASST Lariana), Como, Italy
Pathology Department, SSD Uropathology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
Department of Oncology and Hemato-oncology, University of Milan, and SSD Clinical Psychology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy © Copyright
How to Cite
Enrico Sertoli and the supporting cells of the testis “Morphology is function”
Vol 111 No 4 (2019): Pathologica - Issue 4 - December 2019
Published: Dec 19, 2019
In 1865, Enrico Sertoli, at the age of 23, published an article in his own name entitled: “About the existence of special branched cells in the seminiferous tubules of the human testis”. These were Sertoli’s ideal cells; in this paper he arrived at a perspicacious description of the morphology and function of these cells and in the subsequent articles he investigated the topic of spermatogenesis. Despite the importance of Sertoli’s discovery, the attention of the scientific literature remained very limited after Sertoli’s death for half a century and the partial eclipse finished only in the 1970s of the twentieth century.