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Published: 2024-09-30
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Asbestos Exposure diagnosis in pulmonary tissues

Centre “G. Scansetti” Via Pietro Giuria 9, 10100 Torino
https://orcid.org/0000-0001-5198-1038
SSD Research Laboratories, Research Training Innovation Infrastructure, Research and Innovation Department (DAIRI), Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Via Venezia 16, 15121 Alessandria, Italy
https://orcid.org/0000-0001-8506-7535
SSD Research Laboratories, Research Training Innovation Infrastructure, Research and Innovation Department (DAIRI), Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Via Venezia 16, 15121 Alessandria, Italy
SSD Research Laboratories, Research Training Innovation Infrastructure, Research and Innovation Department (DAIRI), Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Via Venezia 16, 15121 Alessandria, Italy
https://orcid.org/0000-0003-2152-4930
Research Training Innovation Infrastructure, Research and Innovation Department (DAIRI), Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Via Venezia 16, 15121 Alessandria, Italy
Asbestos diagnosis pathologist mineralogist lung

Abstract

The diagnosis of asbestosis requires different criteria depending on whether it is in a clinical or medical/legal setting. In the latter context, only when a “diffuse interstitial fibrosis associated to asbestos bodies (ABs)” is present, it can be said to be asbestosis. Considering the medical/legal setting, the diagnosis must be certain and proven. Unfortunately, it is often difficult to identify ABs by light microscopy (LM), but this does not mean that the diagnosis should be clinically excluded. Other parameters are important, such as working history and/or diagnostic imaging. In addition to LM, normally used for diagnosis, there are other techniques, e.g.: scanning electron microscopy with attached microanalysis microprobe (SEM/EDS), but they require tissue digestion and higher cost. A new approach with micro-Raman spectroscopy and SEM/EDS techniques is able to analyse histological sections without other manipulations that could interfere with analysis of asbestos fibres. In this work, we propose an algorithm for asbestosis diagnosis, especially in the forensic medical field, demonstrating the importance of close collaboration between multiple professionals.

Affiliations

$authorString->getOrcid() => https://orcid.org/0000-0001-5198-1038

$authorString->getFullName() => Donata Bellis

$authorString->getUrl() =>

Donata Bellis

Centre “G. Scansetti” Via Pietro Giuria 9, 10100 Torino
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$authorString->getFullName() => Alessandro Croce

$authorString->getUrl() => https://orcid.org/0000-0001-8506-7535

Alessandro Croce

SSD Research Laboratories, Research Training Innovation Infrastructure, Research and Innovation Department (DAIRI), Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Via Venezia 16, 15121 Alessandria, Italy
esiste orcidID "https://orcid.org/0000-0001-8506-7535" https://orcid.org/0000-0001-8506-7535

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$authorString->getFullName() => Alex Glorioso

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Alex Glorioso

SSD Research Laboratories, Research Training Innovation Infrastructure, Research and Innovation Department (DAIRI), Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Via Venezia 16, 15121 Alessandria, Italy
non esiste orcidID ""

$authorString->getOrcid() => https://orcid.org/0000-0003-2152-4930

$authorString->getFullName() => Marinella Bertolotti

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Marinella Bertolotti

SSD Research Laboratories, Research Training Innovation Infrastructure, Research and Innovation Department (DAIRI), Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Via Venezia 16, 15121 Alessandria, Italy
esiste orcidID "https://orcid.org/0000-0003-2152-4930" https://orcid.org/0000-0003-2152-4930

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$authorString->getFullName() => Antonio Maconi

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Antonio Maconi

Research Training Innovation Infrastructure, Research and Innovation Department (DAIRI), Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Via Venezia 16, 15121 Alessandria, Italy
non esiste orcidID ""

Copyright

© Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology , 2024

How to Cite

[1]
Bellis, D., Croce, A., Glorioso, A., Bertolotti, M. and Maconi, A. 2024. Asbestos Exposure diagnosis in pulmonary tissues. Pathologica - Journal of the Italian Society of Anatomic Pathology and Diagnostic Cytopathology. 116, 4 (Sep. 2024), 207-215. DOI:https://doi.org/10.32074/1591-951X-930.
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