Abstract

Objective. To understand the state of the art of Italian thyroid cytopathology practice, a survey was sent by the Italian Committee of cytopathology to the 846 registered emails of the Italian society of pathology and cytology (SIAPEC) members.

Methods. A survey divided in 4 sections (geographic distribution, pre-analytics, diagnostic work up, molecular testing) was sent to SIAPEC members in April 2023. An additional set of questions regarding molecular analysis was sent to first round participants.

Results. A total of 104/846 (12.2%) SIAPEC members replied to the survey. Non-pathologist physicians performed FNA in the majority of cases (78/104, 75%). The Italian Consensus for the Classification and Reporting of Thyroid Cytology (ICCRTC) system is adopted by most centers (94/104 90,38%), although in 32.6% it was used along with other classifications systems. Only 44/104 (42.2%) of the participants performed molecular tests on thyroid FNA, mostly upon requests from the caring physician (25/41, 61.1%).

Conclusion. This survey offers a snapshot of the current Italian thyroid FNA practice. The volume of thyroid FNA performed is similar to the pre-Covid workload and the ICCRTC is the most frequently adopted classification system. Molecular tests are performed by a significant minority of participants, with different testing modalities and clinical-pathological indications.

Authors

Gennaro Acanfora - Department of Advanced Biomedical Sciences, University of Naples “Federico II”, Naples, Italy

Mariantonia Nacchio - Department of Public Health, University of Naples Federico II,Naples, Italy

Carla Baronchelli - Pathology Unit, Azienda Socio Sanitaria Territoriale(ASST)-Spedali Civili, Brescia, Ita

Amedeo Boscaino - Department of Pathology, Cardarelli Hospital, Naples, Italy.

Carolina Buriani - Anatomic Pathology Unit, University Hospital of Ferrara, 44124 Ferrara, Italy.

Elisabetta Carico - Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital, University of Rome "Sapienza", 00189, Rome, Italy.

Andrea Cavazzana - Pathology Unit, Azienda Sanitaria Toscana Nord Ovest, Via Cocchi 1, 56121, Pisa, Italy.

Anna Maria Cesinaro - Department of Anatomic Pathology, Azienda Ospedaliero-Universitaria Policlinico, Modena, Italy.

Doglione Claudio - Department of Pathology, San Raffaele Scientific Institute. Milan, Italy.

Immacolata Cozzolino - Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.

Anna Crescenzi - Operative Research Unit of Unit of Pathological Anatomy, Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.

Stefania Damiani - Department of Pathology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna 40138 Italy.

Giovanni De Chiara - Anatomic Pathology Unit, San G. Moscati Hospital, 83100 Avellino, Italy

Giselle de Rezende - Department of Anatomic Histopathology and Cytogenetics, Department of Laboratory Medicine, Niguarda Cancer Center, Milan, Italy.

Ludovica De Vincentiis - Department of Pathology, Pescara Hospital, Pescara, Italy.

Guido Fadda - Department of Human Pathology in Adult and Developmental Age "Gaetano Barresi", University of Messina, 98125 Messina, Italy.

Gerardo Ferrara - Pathology Unit, Istituto Nazionale Tumori, IRCCS-Fondazione G. Pascale, 80131 Napoli, Italy.

Flavio Pironi - Operative Unit of Pathologic Anatomy, Local Health Authority of Romagna, St Maria delle Croci Hospital, Ravenna, Italy.

Giacomo Gazzano - Istituto Auxologico Italiano IRCCS, Pathology Unit, Milano, Italy.

Annarita Gencarelli - Department of Pathology, Cardarelli Hospital, Naples, Italy.

Leo Guidobaldi - UOC of Pathologic Anatomy and Cytodiagnostic, Sandro Pertini Hospital, ASL RM2, 00157, Rome, Italy.

Maria Letizia Lai - Department of Cytomorphology, University of Cagliari, 09124 Cagliari, Italy

Gaetano Magro - Department of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", University of Catania, 95123 Catania, Italy.

Grazie Marangi - Unità di Anatomia Patologica, Ospedale SS Annunziata, Taranto, Italy.

Fabio Pagni - Department of Medicine and Surgery, Pathology, University of Milano-Bicocca, IRCCS (Scientific Institute for Research, Hospitalisation and Healthcare) Fondazione San Gerardo dei Tintori, Monza, Italy.

Gianmaria Pennelli - Department of Medicine (DIMED) University of Padua, UOC Anatomia Patologica Azienda Ospedale-Università Padova, Padua, Italy.

Simonetta Piana - Pathology Unit, Arcispedale Santa Maria Nuova, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Via Risorgimento 80, 42124, Reggio Emilia, Italy. simonetta.piana@ausl.re.it.

Michele Pirelli - Unità di Anatomia Patologica, Ospedale SS Annunziata, Taranto, Italy.

Stefano Pizzolitto - Unit of Pathology, University Hospital S. Maria della Misericordia, p.le S. Maria della Misericordia n. 15, 33100 Udine, Italy.

Giuseppina Renzulli - Department of Emergency and Organ Transplantation, Section of Pathological Anatomy, University of Bari "Aldo Moro", Bari, Italy.

Esther Diana Rossi - Department of Pathology, Catholic University of Rome, Rome, Italy

Silvia Taccogna - Pathology Unit, Regina Apostolorum Hospital, Albano Laziale (RM) 00041, Italy

Silvia Uccella - Department of Pathology, Humanitas Research Hospital, Rozzano, Milan, Italy.

Clara Ugolini - Department of Surgical, Medical, Molecular Pathology and Critical Area, Unit of Pathology, University Hospital of Pisa, Pisa, Italy.

Andrea Vecchione - Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital, University of Rome "Sapienza", 00189, Rome, Italy.

Elena Vigliar - Department of Public Health, University of Naples Federico II, Naples, Italy

Marco Volante - Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant'Andrea Hospital, University of Rome "Sapienza", 00189, Rome, Italy.

Roberta Zappacosta - Department of Oncology and Experimanetal Medicine, Section of Cytopathology "G. d'Annunzio" University of Chieti-Pescara Via dei Vestini, 66100 Chieti Scalo, Italy.

Francesco Alfredo Zito - Anatomy Pathology, IRCCS Istituto Tumori Giovanni Paolo II Bari.

Giovanni Tallini - 35Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy; 36Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy

Giancarlo Troncone - Department of Public Health, University of Naples Federico II,Naples, Italy

Claudio Bellevicine - Department of Public Health, University of Naples Federico II,Naples, Italy

How to Cite
Acanfora, G., Nacchio, M., Baronchelli, C., Boscaino, A., Buriani, C., Carico, E., Cavazzana, A., Cesinaro, A. M., Claudio, D., Cozzolino, I., Crescenzi, A., Damiani, S., De Chiara, G., de Rezende, G., De Vincentiis, L., Fadda, G., Ferrara, G., Pironi, F., Gazzano, G., Gencarelli, A., Guidobaldi, L., Lai, M. L., Magro, G., Marangi, G., Pagni, F., Pennelli, G., Piana, S. ., Pirelli, M., Pizzolitto, S., Renzulli, G., Rossi, E. D., Taccogna, S., Uccella, S., Ugolini, C., Vecchione, A., Vigliar, E., Volante, M., Zappacosta, R., Zito, F. A., Tallini, G., Troncone, G., & Bellevicine, C. (2025). Trends in Thyroid Fine-Needle Aspiration Cytology - Results from the Italian Cytopathology Committee National Practice Survey: Trends in Thyroid FNAC – 2022 Italian Survey. Pathologica - Journal of the Italian Society of Anatomic Pathology and Diagnostic Cytopathology, 117(4). https://doi.org/10.32074/1591-951X-N1295
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