Abstract

Leishmaniasis is an infectious disease caused by a protozoon of the genus Leishmania. It can manifest as cutaneous, mucosal, localized lymphadenitis forms or it can result as multiorgan involvement. In this article we present the case of a 59-year-old male with a polypoid mass attached to the septum at the right nasal cavity and symptoms as nasal congestion, hyposmia and anterior rhinorrhea. Histological sections of the mass showed oval-shaped inclusions in the cytoplasm of histiocytes suspicious for Leishmania amastigotes. The diagnosis was confirmed by detection of Leishmania complex DNA with polymerase chain reaction (PCR).

Downloads

PDF
Authors

Federica Filipello - Vita-Salute San Raffaele University, Milan, Italy; Department of Pathology, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy

Daniela Finocchiaro - Vita-Salute San Raffaele University, Milan, Italy; Department of Pathology, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy

Alessandro Vinciguerra - Vita-Salute San Raffaele University, Milan, ItalyDepartment of Otorhinolaryngology, IRCCS San Raffaele Scientific Institute, Milan, Italy;

Sara Racca - Department of Microbiology and Virology, IRCCS San Raffaele Scientific Institute, Milan, Italy

Claudio Doglioni - Vita-Salute San Raffaele University, Milan, Italy; Department of Pathology, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy;

Federica Pedica - Vita-Salute San Raffaele University, Milan, Italy; Department of Pathology, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Copyright

Copyright (c) 2025 Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology

How to Cite
Filipello, F., Finocchiaro, D., Vinciguerra, A., Racca, S., Doglioni, C., & Pedica, F. (2025). A tricky nasal polyp. Pathologica - Journal of the Italian Society of Anatomic Pathology and Diagnostic Cytopathology, 117(2). Retrieved from https://www.pathologica.it/article/view/1352
  • Abstract viewed - 13 times
  • PDF downloaded - 4 times