Summary

Tumour-to-tumour metastasis (TTM) refers to a malignant tumour metastasizing to a second, distict tumour. It is a rare phenomenon and the most common donor organs are the lung and breast. Here in, we report a case of TTM metastasis of breast carcinoma metastasizing to an adrenocortical adenoma (ACA) in a 40-year-old woman. To the best of our knowledge, this is the first case in which TTM of breast carcinoma metastasizes to an ACA.

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Authors

Maria Luísa Sacramento - Department of Pathology, Unidade Local de Saúde São João, Porto, Portugal; Faculty of Medicine, University of Porto, Porto, Portugal

João Menino - Faculty of Medicine, University of Porto, Porto, Portugal; Department of Endocrinology, Diabetes and Metabolism, Unidade Local de Saúde São João, Porto, Portugal

Vitor Proa - Department of Pathology, Unidade Local de Saúde São João, Porto, Portugal

Bárbara Viamonte - Department of Radiology, Unidade Local de Saúde São João, Porto, Portugal

João Sérgio Neves - Faculty of Medicine, University of Porto, Porto, Portugal; Department of Endocrinology, Diabetes and Metabolism, Unidade Local de Saúde São João, Porto, Portugal

Elisabete Rios - Department of Pathology, Unidade Local de Saúde São João, Porto, Portugal; Faculty of Medicine, University of Porto, Porto, Portugal; Institute for Research and Innovation in Health (i3s), Porto, Portugal

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Copyright

Copyright (c) 2026 Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology

How to Cite
Sacramento, M. L., Menino, J. ., Proa, V. ., Viamonte, B. ., Neves, J. S. ., & Rios, E. . (2026). Breast carcinoma metastasizing to an adrenocortical adenoma: a case of tumour-to-tumour metastasis. Pathologica - Journal of the Italian Society of Anatomic Pathology and Diagnostic Cytopathology, 118(2). https://doi.org/10.32074/1591-951X-2228
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