Abstract

Dear Editor,

it is with a great pleasure that we want to submit this very interesting case about the unique coexistence of a lung adenocarcinoma and diffuse large lymphoma in the same lung nodule. The nodule was found accidentally, and the patient was asymptomatic for both the oncological pathologies. At anatomo-pathological analysis the histological features of both lesions were identified. To the best of our knowledge, this is the first case in which the two tumors are together in the very same nodule.

A lung nodule in the right upper lobe was occasionally detected in a 74-year-old man.

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Authors

Carolina Sassorossi - fondazione policlinico universitario agostino gemelli, IRCCS

Qianqian Zhang - 2. Division of Anatomic Pathology and Histology, Fondazione Policlinico Universitario A. Gemelli - IRCCS, 00168 Rome, Italy

Alessandra Cancellieri - 2. Division of Anatomic Pathology and Histology, Fondazione Policlinico Universitario A. Gemelli - IRCCS, 00168 Rome, Italy

Elena Maiolo - 3. Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

Marco Chiappetta - Thoracic Surgery Unit, University “Magna Graecia”, Catanzaro, Italy

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Copyright

Copyright (c) 2025 Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology

How to Cite
Sassorossi, C., Zhang, Q., Cancellieri, A., Maiolo, E., & Chiappetta, M. (2025). A lung nodule showing both adenocarcinoma and diffuse large lymphoma: a pathological anatomy surprise. Pathologica - Journal of the Italian Society of Anatomic Pathology and Diagnostic Cytopathology, 117(4). https://doi.org/10.32074/1591-951X-N904
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